8 Vegan Thanksgiving Main Dish Recipes

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A good vegan Thanksgiving main dish should feel like the center of the meal, with enough substance and flavor to anchor the rest of the menu. These eight recipes include sliceable roasts, seitan centerpieces, stuffed squash, and a mushroom lentil loaf, so you can choose a main that fits your cooking schedule.

This is a mixed-publisher collection. Follow each linked recipe for its complete ingredients, timing, and instructions. Pair your choice with these vegan Thanksgiving sides and vegan Thanksgiving appetizers.

Collage of vegan Thanksgiving main dishes

8 Vegan Thanksgiving Main Dish Recipes

Vegan Holiday Roast from Vegan Huggs

This seitan roast is seasoned with garlic, rosemary, sage, and thyme, then finished with a glaze. Its sliceable shape makes it easy to portion alongside mashed potatoes and mushroom gravy.

Sliced vegan holiday roast with herbs and glaze

Glazed Tofu Roast from Yup, It’s Vegan

Tofu becomes a holiday-style roast with a sweet and savory glaze. This option gives the menu a firm, sliceable centerpiece without using seitan.

Glazed tofu roast sliced on a serving board

Vegan Pork Tenderloin Roast with Apples and Onions from Planted365

This plant-based roast is served with apples and onions for a savory-sweet main course. The long, sliceable presentation works well when you want a traditional roast-style centerpiece.

Vegan tenderloin roast served with apples and onions

Maple Glazed Holiday Vegan Ham from Sunnyside Hanne

This vegan ham is glazed with maple and presented with fruit and whole cloves. Choose it when you want a smoky, sweet centerpiece that can be sliced at the table.

Maple glazed vegan holiday ham with fruit and cloves

Stuffed Roasted Butternut Squash from It Doesn’t Taste Like Chicken

Roasted butternut squash holds a filling of wild rice, vegetables, cranberries, walnuts, and herbs. It adds color to the table and offers a main dish built around vegetables and grains.

Roasted butternut squash filled with wild rice, vegetables, and cranberries

Slow Cooker Vegan Corned Beef from Plant Power Couple

This homemade seitan roast gets its color from beets and finishes in the oven with a black pepper crust. Much of the cooking happens in the slow cooker, which can help when oven space is tight.

Sliced slow cooker vegan corned beef with black pepper crust

Vegan Chick’n from Full of Plants

This plant-based chick’n has a fibrous, sliceable texture. It is a useful choice for cooks who want a homemade centerpiece that can stand in for a familiar holiday roast.

Sliced homemade vegan chick'n roast

Mushroom Lentil Loaf with Cranberries from A Virtual Vegan

Lentils, mushrooms, and walnuts form this loaf, while cranberries add a bright holiday topping. It gives the table a hearty centerpiece without relying on a mock-meat roast.

Mushroom lentil loaf topped with cranberries

A Store-Bought Vegan Thanksgiving Main Dish

If you would rather save the prep time for sides and dessert, a Tofurky Roast and Gravy is a ready-made option. Check the package directions and availability at your local store before planning the rest of the oven schedule.

Tofurky holiday roast served with gravy

How to Choose Your Vegan Thanksgiving Main Dish

Start with the cooking method. A slow cooker recipe can leave the oven open for casseroles, while a roast or loaf may be easier to slice and serve to a larger group. Stuffed squash brings vegetables, grains, and fruit together in one dish. Check which recipes can be prepared ahead, then build your side-dish schedule around the main that needs the most oven time.

Complete the menu with vegan green bean casserole, vegan mushroom stuffing, or one of these vegan Thanksgiving desserts.

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